Micellar nanoparticle formation via electrostatic interactions for delivering multinuclear platinum(II) drugs.
نویسندگان
چکیده
Nanoparticles formed via electrostatic interactions between methoxy-polyethylene glycol-block-poly(glutamic acid) (MPEG-PGA) and a multinuclear platinum(II) drug, di-cisPt, exhibit efficient platinum loading, improved cellular uptake, in vitro cytotoxicity, and enhanced in vivo efficacy.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 42 شماره
صفحات -
تاریخ انتشار 2013